Cell Culture Profiling method package adds metabolites characteristic of CHO cells, which are frequently used in the manufacture of monoclonal antibodies. Together with existing analytes, including amino acids, vitamins, basal medium compounds, and other metabolites, this method package enables simultaneous analysis of 144 compounds in less than 20 minutes without complex method development.
Metabolites present in both the cell medium supernatant and within cells can be analyzed using the same optimized chromatography and mass spectrometry conditions.
This product makes it easy to visualize the time-course changes of up to 144 compounds from culture supernatant and cellular extracts collected at intervals.
Volcano plots, principal component analysis, hierarchical clustering, and other analyses can easily be performed using the included Multi-omics Analysis Package. In addition, changes in the amount of compound over time can be visualized with a few simple operations, so the process from measurement to data analysis can be implemented seamlessly.