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LabChip GXII Touch HT Protein Characterization System

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LabChip GXII Touch HT Protein Characterization System

LabChip GXII Touch HT Protein Characterization System Spincotech
The LabChip™ GXII Touch™ protein characterization system is a complete solution enabling the rapid characterization of both protein and nucleic acid samples. Leveraging microfluidic capillary electrophoretic (CE) separation technology, it enables rapid characterization with minimal sample preparation setup and sample input volume.

LabChip GXII Protein Characterization System Benefits

  • Ease of use
  • High throughput
  • Flexible
  • Small footprint
  • Cost efficient
  • Fast analysis
  • Increased efficiency
  • Supports testing in a streamlined and reproducible GMP-compliant environment
LabChip GXII protein Product Image Spincotech

Coming soon... Empower on LabChip!

Take full control of your nucleic acid and protein assays on the LabChip GX Touch and LabChip GXII Touch systems with Waters® Empower™ software. Seamlessly acquire and analyze your data with a single software with the new LabChip Empower™ v1.0 driver.

Improved Efficiency

By running LabChip systems directly from the Empower software, labs can streamline workflows, reduce hands-on time, and boost productivity.

Data Integrity

Ensure your data is securely stored and readily available for review, analysis, and audit through the Empower software’s robust compliance features.

Future-Proof

LabChip Empower driver v1.0 is fully compatible with the Empower software, ensuring your system is ready for future software updates and advancements.

Empower on LabChip Spincotech

Overview

LabChip GXII Touch Instrument Simplifies Sample Analysis
User friendly operation:
  • Load sample plate and chip
  • Select samples (up to 384 in a run)
  • Select assay type
  • Touch ‘Run’ to start
  • Automatically export data directly to your network or LIMS system
Observe runs in real time:
  • Sample analysis in as few as 42 seconds
  • View electropherogram in real time during data collection
  • Overlay collected data to compare sample profiles
  • Select from various run time analytical feature annotations
See data in real time or export for later analysis:
  • Choose “display” in E-gram, virtual gel, or data table format (Figure 1)
  • Pull multiple archived plates into data review or analytical comparisons
  • Apply data mining filter functions on key attributes
  • Highlight expected peaks
  • Track relevant user access and data history parameters with FDA 21 CFR Part 11 compatible software
Easy Set-up for Protein and Nucleic Acid Characterization

The LabChip GXII Touch protein characterization system operator controls are designed to allow users to easily set up and execute a run in as few as three easy steps. Run templates can also be imported with the operator control features. Run templates can include well selections, sample names, peak tables, which facilitate operator ease of use, and data can be automatically exported to network or LIMS directories for subsequent analysis. Every instrument comes with a full software package for data review, allowing analysis from current or archived data sets.

Designed To Facilitate Integration Of Quality By Design Initiatives Into Workflow

The LabChip GXII Touch protein characterization system offers rapid quantification and quality control throughout biotherapeutics and genomic workflows. For example, automating the characterization process allows multiple critical quality attributes to be obtained significantly faster. Researchers can now screen for optimal protein characteristics earlier in the process and integrate Quality by Design initiatives into their biotherapeutics development workflow.

21cfr Part 11 Compatible Software Is Available With The LabChip GXII Touch Protein Characterization System

LabChip GXII Touch and Reviewer Software contain built-in technical controls and features specifically designed to support FDA 21 CFR Part 11 regulations. These features include a shared user account database, access controls, device check, enforced sequencing of run steps, audit trails, record copying, record retention, system documentation, and electronic signature controls.

To assist in your compliance planning, LabChip GxP Security Software is available which allows the LabChip GXII Touch protein characterization system to run in an environment consistent with CFR21 Part 11 compliance and validation (Figure 2). This includes access security, data security and verification, and a complete set of audit logging functionality.

LabChip CE: How Does it Work?
LabChip CE is performed on a small, microfluidic chip. Prior to analysis, reagents are loaded into the individual wells of the chip. These wells are connected to tiny microchannels about the size of a human hair etched within the quartz microfluidic chip. When the chip is loaded into the LabChip GXII Touch protein characterization system, the chip’s wells interface with platinum electrodes that provide voltage and current control. The instrument moves the microtiter plate directly under the chip’s capillary ‘sipper’, and approximately 150 nL of sample is aspirated onto the chip. Sample staining and destaining are performed automatically on the instrument platform. Individual sample analytes are separated electrophoretically and the bands detected via laser induced fluorescence in the capillaries of the chip. Sizing and concentration for each band are determined using ladder and internal markers. Rinsing the sipper between samples minimizes cross contamination.
Specifications
Physical Specifications
Dimensions51.0 cm (W) x 49.0 cm (D)
Other Specifications
21CFR Compatible
Yes
Application
Protein/DNA/RNA Characterication
Automation Compatible
Yes
Brand
LabChip GXII
Model
LabChip GXII Touch HT Protein Characterization System
Research Areas
Translational Research