The LabChip cfDNA assay is a robust, high-throughput, automated, and easy-to-use assay that delivers digital assessment of cfDNA concentration and sizing of up to 96 cfDNA samples in one chip preparation in less than 1.5 hours, and provides qualitative information about contaminants in the cfDNA sample.
The LabChip cfDNA Assay incorporates a 50 base pair DNA as an internal standard (that is closer in size to the cfDNA smears) instead of a high molecular weight upper marker typically used for DNA quantitation to correct the sample injection bias and enable improved quantitation accuracy. Faster analysis and the ability to analyze cfDNA in the low pg/µL range.
The LabChip cfDNA Assay is capable of detecting cfDNA samples with concentrations as low as 25 pg/μL (S/N>3), and the assay has a linear range of 50-1000 pg/μL. Quantitation accuracy is within ±20% of the target concentration and sizing accuracy is within ±10% of the target size.
This assay can be used to analyze cfDNA samples extracted using chemagic™ cfDNA extraction kits and other commercially available extraction kits.
The LabChip cfDNA assay enables high resolution sizing of cfDNA mono-, di-, and tri-nucleosomes in ~ 1 minute samples.
| Application | DNA Analysis |
|---|---|
| Automation Compatible | Yes |
| Instrument Compatibility | LabChip GXII Touch |
| Sample Type | DNA |
| Shipping Conditions | Shipped in Blue Ice |
| Technology | Microfluidic Electrophoresis |
| Unit Size | 1,000 samples |