Next-generation Nexera X4 UHPLC achieves an incomparable level of analytical performance through cutting-edge fluid control technology providing exceptional solvent delivery consistency, even for fast analysis under ultra-high-pressure conditions.
Nexera X4 UHPLC Systems incorporate proprietary Nexflow technology achieving the lowest degree of peak broadening* in the industry without changing the internal diameter of the flow lines resulting in ultra-sharp peaks and outstanding separation performance. An overall increase in column performance by minimizing broadening of sample peaks outside the column improves the theoretical plate numbers even for analytes which are weakly retained.
and 78% shorter compared to those with typical HPLC and existing UHPLC-like systems, respectively, resulting in up to 14 times higher laboratory productivity. Superior gradient reproducibility coupled with highly consistent solvent delivery results in excellent retention time reproducibility.
Through analytical miniaturization, exceptionally low solvent quantities are consumed while maintaining superior analytical performance.
Micro-injection – Good repeatability with even 1µL injections
Highly precise solvent delivery – Small internal volumes enable gradient runs with microbore columns
Reduced Peak broadening – Nexflow technology offers sharp peaks
LCMS-8060RX triple quad coupled featuring positive and negative ionization switching in 5 msec with UFswitching™ technology in combination with Nexera X4, offers the next-generation LC-MS platform that delivers unmatched throughput and reliability. The platform is ideal for pharmacokinetic analytical workflows where fast, reliable analysis are of prime importance.