Analysis of Voglibose by Post-Column Derivatization Method

Automated Analysis of Thirty-seven DL-amino Acids using Liquid Chromatography with Fluorescence Detection and Its Application to Liquor Samples

Automatic Optimization of Gradient Conditions by AI Algorithm for Impurity Analysis

Automatic Optimization of Sample Solvent Composition for Achieving Sharp Peak Shapes

Determination of Dexamethasone and its organic impurities content as per USP monograph UHPLC method

Quantitative Analysis of Catechins in Tea Leaves

OUR SERVICES

Let’s Research
More Science

UHPLC with IoT & AI Features N-Series, The NextGen UHPLC

N-Series Spincotech

UHPLC with IoT & AI Features N-Series, The NextGen UHPLC

A New Benchmark of Intelligence
A New Benchmark of Design
A New Benchmark of Efficiency

N-Series UHPLC system blends cutting edge Artificial Intelligence (AI) and Internet of Things (IoT) enhancements to achieve improved operational efficiency and reliable LC analysis.  Automated functions such as monitoring and diagnosing itself, handle any issues during data acquisition without user input.  Reservoir tray weight sensors measure the real time volume of mobile phase in the bottle and alerts are sent to users if quantities go down below pre-set levels.  Shimadzu Nexflow technology minimizes the phenomenon of extra-column dispersion, without changing the inner diameter or length of the piping in the UHPLC system. By suppressing peak band dispersion, UHPLC analysis with a high degree of separation and high sensitivity is achieved.

  • Power of AIAnalytical Intelligence
    • New Smart Flow Control during Start-up and shutdown
    • Auto diagnosis and Auto-recovery from flow anomalies
    • Remote Maintenance & Laboratory Management
    •  Mobile Phase Monitor (MPM) with true gravimetric data for quantity.
  • Superb Injection Precision over wide sample volumes
  • Dew-Free Autosampler with lowest carry over
  • PDA with the highest dynamic range, TC Optics and UV Cut-Off Filters
  • Method Scouting through 6 Column & 8 Mobile Phase Switch
  • The best Front-End for Mass Spectrometry
  • High Efficiency LC with up to 130 MPa pressure tolerance

21 CFR Part 11 compliant LabSolutions software

Auto-Diagnostics and Recovery 1
Auto-Diagnostics and Recovery
FlowPilot Protects Columns Spincotech
Flow Pilot Protects Columns

Each column is recognized by an individual ID, and stats such as pressure and injection number are automatically recorded in the database and linked to each measurement data file. SIL-40 autosampler can process the entire injection cycle time in seven seconds, twice as fast as the previous model.  Continuous analysis can be carried out on up to 44 MTPs (using 3 PLATE CHANGERS). Co-Injection Automation function can be used to perform derivatization within the sample loop before injection, resulting in excellent peak shapes.

Stable Baseline Spincotech
Stable Baselines and Higher Detector Reproducibility

Intelligent Peak Deconvolution Analysis (i-PDeA) technique extracts a single peak from co-eluted peaks and quantitates it by exploiting the differences in spectra between each compound.  The SPD-M40 detector provides high sensitivity and linearity (up to 2.5 AU). The UV cut-off filter resulted to be useful for quantitative determination of components that are easily degraded by wavelengths in the UV range, particularly improving quantitation accuracy in the low concentration range.

N-Series UHPLC uses over 80% less electricity when in standby mode and features a compact design that is two thirds the size of Shimadzu’s previous model.