LyobeadPRO – Benchtop Precision Lyobead Generator
The LyobeadPRO is a benchtop device designed to produce high quality lyobeads in a controlled environment within the settings of a traditional laboratory. The versatility of the device provides an ideal tool for both R&D purposes and upscale for production use. High-quality bead production is provided by utilising accurate fine dosing control, ensuring each bead contains the same amount of material and is consistent in size and shape.
With single or dual droplet nozzles and the in-built ‘drawback’ process, lyobeads with viscous or non-viscous formulations can be efficiently produced within a sieved container held within the liquid nitrogen. The sieved bead collection pan is easily retrieved from the dewar and allows for dispensing of the frozen beads into freeze drying vials or trays in a safe manner. The locked dispensing nozzles and segmented rotating head located inside the dewar ensures snap freezing is performed at the correct height without risk of amalgamation (clumping) of beads within the LN2. Batch sizes of up to 12,000 beads/hour can be produced with dual nozzle output.
Key features for users offered by the LyobeadPRO:
- Generate 100 – 10,000 beads/day for both R&D and production use with precise volume and shape.
- From 5ul to 50ul sizes
- Volume precision 0.10%
- Unparalleled ease of use and simplicity of design
- Single or dual nozzle operation, and easy to fit dispensing nozzles.
- Benchtop device that can be operated inside or out of a nitrogen-controlled environment
- Rotation of the segmented LN2 dewar is controlled to avoid clustering of the droplets during snap freezing within the liquid nitrogen.
- Easy product formulation testing
- Safe collection of frozen beads within sieve container.
- A count of the bead numbers is displayed on the easy to read controller.
- An in-built priming facility allows for easy interchange from product to product.