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MyMassMP

MyMassMP Spincotech

Assess protein sample purity and homogeneity in minutes with mass photometry using only nanograms of sample.

Know that your sample is ready. The Refeyn MyMass™ mass photometer (MyMassMP) gives you fast, accurate assessment of purity and homogeneity – so you can proceed to cryo-electron microscopy (cryo-EM), native mass spectrometry (MS), surface plasmon resonance (SPR), or biolayer interferometry (BLI) with confidence.

MyMass makes it easy to:
  • Verify sample purity
  • Assess sample homogeneity
  • Check oligomerization state
  • De-risk costly experiments

Who uses MyMassMP

In structural biology, every experiment counts. MyMass is designed for structural biologists and the teams that support them – to give them the clarity and efficiency they need so they can focus on discovery. MyMass is built for researchers who are regularly:
Purifying proteins
  • MyMass confirms purity and homogeneity
  • Gain insight from single-molecule resolution that bulk methods, like SEC, SDS-PAGE, or DLS, cannot match
Running high-value experiments
  • MyMass reveals poor sample quality before it can ruin cryo-EM, native MS, SPR, or BLI experiments
  • Know your sample is ready before you commit – saving time, cost, and precious material
Screening and optimizing sample conditions
  • MyMass tests multiple conditions in minutes
  • Measurements are run in native buffer – no column interactions, no denaturation
  • Rapidly identify the preparation that is mostly likely to succeed

Key data

Got a minute? That’s all it takes to find out if your sample is ready.

Specifications:
  • Results in 1 minute. Fast enough to screen multiple conditions in a single session.
  • 55 kDa – 3 MDa mass range. Suitable for a broad range of proteins and complexes.
    ±5% mass precision. Reproducible results, so you can make go/no-go decisions with confidence.
  • ±10% mass error. Accuracy with a single measurement – no repeats required.
  • Ready to measure in 1 minute from power-on. Just walk up and measure.
MyMass_results_screen Key data Spincotech
Rapid turnaround
  • From power-on to results in just minutes​
  • 1 minute per measurement
Low sample consumption
  • 30 µL at nM concentration​​​
  • Single-molecule sensitivity reveals species at 5% abundance
In solution
  • Analysis in native conditions​
  • Compatible with many buffers

Software that guides you from sample to result

MyMass features onboard software with a guided workflow. A touchscreen interface walks you through every step, with diagrams, videos, and built-in help so even occasional users can get results with confidence.
  • Guided workflows: Step-by-step instructions with diagrams and videos make MyMass simple to walk up and use
  • Simple, powerful analysis: Mass distribution, automatic peak fitting, and a clear results table give you everything you need to assess your sample
  • Built-in support: Extensive help, tools, and FAQs are always at hand
Software that guides you from sample to result Spincotech