With different pore sizes, Shim-pack Bio Diol LC columns are effective for analysis of aggregates and fragments of mAb, oligonucleotides and carbohydrates.
| Shim-pack Bio Diol | Diol-60 | Diol-120 | Diol-200 | Diol-250 | Diol-300 |
|---|---|---|---|---|---|
| Particle | Silica | ||||
| Ligand | Dihydroxypropyl (Diol) | ||||
| Particle Size | 3 μm, 5 μm | 2 μm, 3 μm, 5 μm | 3 μm | 2 µm, 3 µm, 5 µm | |
| Pore Size | 6 nm | 12 nm | 20 nm | 25 nm | 30 nm |
| pH Range | 5.0 – 7.5 | ||||
| Molecular Weight Range | below 10,000 | 1,000 – 100,000 | 5,000 – 300,000 | 100,000 – 700,000 | 20,000 – 1,000,000 |