By localizing transcripts with nanometer precision, MERFISH 2.0 reveals the spatial organization of genes, cell states, and interactions, creating molecular maps that link expression to function.
Acquire high-quality, reproducible spatial data from even the most difficult samples, including archival FFPE and fresh-frozen tissues.
Improved sensitivity detects more RNA molecules with uncompromised specificity and subcellular resolution, revealing subtle expression gradients.
Generate richer datasets with more cells passing quality filters, enabling higher transcript detection and deeper biological context per sample.
Distinguish rare and abundant cell populations across complex tissues to illuminate the mechanisms that drive health and disease.
Explore molecular and cellular crosstalk within intact tissue architecture to inform disease models and therapeutic discovery.
Built on decades of MERFISH spatially resolved transcriptomics innovation, MERFISH 2.0 delivers scalable, high-confidence results.
MERFISH 2.0 on the MERSCOPE Ultra platform resolves tens of thousands of RNA targets per sample at true single-cell resolution, revealing cell states and spatial organization.
InSituPlex multiplex immunofluorescence quantifies protein markers on the same types of specimens, including FFPE.
Together, these technologies deliver true multiomics that turn static sections into actionable spatial biology for neuroscience, tumor profiling, immune research, and many more fields of research.

Detect brain cell types and circuits in intact tissue with MERFISH spatial transcriptomics or multiplex proteomics.

Profile the tumor microenvironment: map up to 1,000 genes at single-cell scale and quantify checkpoint proteins with multiplex IF to inform therapy response.

Map immune niches with spatial transcriptomics or multiplex proteomics to profile cell states, interactions, and checkpoint/activation markers in context.
Vizgen enables high-resolution spatial transcriptomics using MERFISH technology to map thousands of RNA molecules within intact tissues at single-cell resolution, delivering deeper insight into tissue architecture and cellular function.