Shimadzu Single Quad LC-MS has been designed keeping in mind ‘ease of use’ as an LC detector in all aspects of design, instrument control, and analysis data. As with other LC detectors, LCMS- 2050 can be integrated into any Shimadzu LC architecture, whether it is a high throughput analytical system, a preparative LC with fraction collection, or even a legacy model. And it as simple to use as other LC detectors. Only the simplest of acquisition parameters are required to obtain reliable and sensitive detection. The LCMS-2050 is compact, provides high speed and high sensitivity over a wide mass range. It is ideal for routine monitoring of reactions during process development, impurity analysis and serves as a very useful tool for ‘mass-directed purification’ using Prep LC workflows.