Read More Development of a Highly Sensitive and Automated Immunoassay for Brain Derived pTau-217: Analytical Performance in Human Plasma Samples Poster Blood-based biomarkers are increasingly valuable for early detection and monitoring of Alzheimer’s Disease, and while plasma pTau-217 shows high accuracy for amyloid-PET positivity, the fact that only ~20% is brain-derived highlights the need for highly sensitive assays targeting brain-derived pTau-217 to better reflect disease pathology. NULISA™ Technology The NULISA™ Platform combines attomolar-level sensitivity with high-plex proteomic analysis for ultra-sensitive biomarker detection and quantification. Powered by proprietary immunocomplex capture technology and next-generation sequencing, it enables scalable, high-resolution protein profiling from minimal sample volumes. Contact Us arrow_forward arrow_back

Benefits Of Nulisa

Ultra High Sensitivity Spincotech

Ultra High Sensitivity

Detect what matters most, in the samples that most matter

Attomolar sensitivity for detection and baseline quantitation of critical biomarkers from non-invasive sample types as well as remote sampling devices.

High Specificity Spincotech

High Specificity

Distinguish between isoforms and PTMs

Assays developed to detect individual isoforms and a variety of post-translational modifications. Antibodies are selected for reduced cross reactivity with known homologs.

Scalable Multiplex Spincotech

Scalable Multiplex

Discover and validate on one platform

Flexible, scalable chemistry provides the ability to focus in on a single target, or multiplex hundreds to potentially thousands of targets in a single sample on one platform.

Broad Dynamic Range Spincotech

Broad Dynamic Range

Measure Changes Across the Biological Spectrum

With single plex up to 7 logs and multiplex up to 12 logs of dynamic range, NULISA enables quantitation across a broad range of biological expression levels without the need for dilution.

Automation Spincotech

Automation

Generate reproducible data quickly with minimal effort

Fully automated workflow with <30 minutes of total hands-on time, can processes up to 288 samples per run batch.

Fully Automated Workflow

Single-plex results in ~8 hours and multiplex results in ~16 hours with <30 minutes total hands-on time with the ARGO™ HT System

Fully Automated Workflow Spincotech

our expertise

About Alamar Biosciences

Alamar Biosciences is a precision proteomics company focused on ultra-sensitive biomarker detection technologies for translational research, clinical studies, and precision medicine applications. Its proprietary NULISA™ and ARGO™ platforms combine attomolar sensitivity with high multiplexing to enable deep protein profiling from minimal sample volumes across neurology, oncology, immunology, and inflammatory disease research.

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Plex Protein Detection