SP Hull LyoConstellation Freeze Dryer
Hull designs, manufactures, installs, and services cGMP vacuum freeze drying equipment for the reliable lyophilization of a wide range of pharmaceutical and biotech products. We have a broad line of standard freeze dryer models and ancilliary equipment such as Clean-In-Place skids and autoloading and unloading systems. We also provide highly customized equipment upon request, utilizing fifty-plus years of industry experience and our in-house engineering and fabrication resources.
Hull offers full System Integration and Factory Acceptance testing, and IQ, OQ, and SIT documentation packages using the GAMP 5 model. Installation services and after-sale technical service and replacement parts are also available
Specification
Lyophilizer Selection Guide
These freeze dryers are only our starting points – we will be glad to use our 50-plus years of experience to custom engineer a freeze dryer to your exact requirements.
Click on a model number to view the specification sheet. (Learn how to read a Hull Freeze Dryer Model Number)
| Model | Shelf Size W x D inch (mm) | Product Area sq.ft (sq.m) | Ice Capacity Kgs |
|---|---|---|---|
| 24FS40 | 24 x 36 (610 x 914) | 24 (2.23) | 40 – internal |
| 24FXS50 | 24 x 36 (610 x 914) | 24 (2.23) | 50 – external |
| 48FS75 | 24 x 36 (610 x 914) | 48 (4.46) | 75 – internal |
| 48FXS75 | 24 x 36 (610 x 914) | 48 (4.46) | 75 – external |
| 72FS100 | 36 x 48 (914 x 1219) | 72 (6.69) | 100 – internal |
| 72FXS100 | 36 x 48 (914 x 1219) | 72 (6.69) | 100 – external |
| 120FS175 | 36 x 48 (914 x 1219) | 120 (11.15) | 175 – internal |
| 120FXS200 | 36 x 48 (914 x 1219) | 120 (11.15) | 200 – external |
| 220FXS450 | 48 x 60 (1219 x 1524) | 220 (20.44) | 450 – external |
| 450FXS800 | 60 x 72 (1524 x 1829) | 450 (41.81) | 800 – external |
How to read a Hull Freeze Dryer Model Number
Example: 650 F X S 1100 – SS 25C
The 650 indicates the usable shelf product area in square feet. We have made freeze dryers from 2 ft22 (.19 m22) to 1080 ft22 (100 m22). So far.
The F refers to a freeze dryer as opposed to a shelf dryer. We also make shelf dryers.
The X indicates a freeze dryer with an external ice condenser. We make both internal and external ice condensing systems.
The S refers to a freeze dryer with shelf stoppering capability. We also make freeze dryers with fixed shelves. Our standard stoppering pressure is adjustable to 10 lbf/in22 (7031 kg/m22); our highest has been 40 lbf/in22 (28123 kg/m22). So far.
The 1100 indicates the lyophilizer’s ice condensing capacity as liters of water. We have made condensing systems with capacities from 5 liters to 1200 liters. So far.
The SS indicates stainless steel construction of all product contact and cleanroom surfaces.
The 25C indicates an ASME Code Certified pressure rating of 25 lbf/in2 gauge. Hull designs and fabricates its vessels in-house and is certified to the American Society of Mechanical Engineers Section VIII Division 1 requirements for Unfired Pressure Vessels. Our standard vessels are rated for steam at 20 psig (1.1.38 bar), 25 psig (1.72 bar), or 30 psig (2.07 bar) dependent upon the customer’s requirements.
