ONSO SYSTEM Short-read sequencing

A GROUNDBREAKING NEW SEQUENCER

The Onso system is an innovative benchtop short-read DNA sequencing platform with an extraordinary level of accuracy using PacBio sequencing by binding (SBB) technology. Ultra-high Q40+ data quality allows you to break through limits of detection.

Greater level of sensitivity to detect rare variants
Reduced requirement for sequencing coverage depth versus SBS sequencers
Contiguous reads through homopolymer and difficult to sequence regions
Low duplication rate, no index hopping
Rapid conversion of existing P5/P7 libraries for sequencing on the Onso system

15× higher accuracy than other benchtop sequencers

SBB chemistry to deliver ultra-high quality, highly accurate, and exceptionally sensitive detection of cfDNAs.

Unprecedented sensitivity

Delivering the ability to identify biomarkers missed by other sequencing platforms.

Q40+ performance provides high quality results at lower read depth than SBS.

Less sequencing per sample allows reduced cost and increased throughput.

Seamless workflow integration

Designed with key accessories and the flexibility to integrate with existing short-read tools:

  • Library conversion kit
  • PacBio native library prep kits (HMW and fragmented DNA preparation)
  • Blocking oligos for hybridization capture methods
  • Library amplification kit
  • Library quantification kit
  • Lambda sequencing control library (spike-in library)
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