Mobius Electrophoretic Light Scattering Detector

Wyatt Technology’s Mobius™ is the first and only light scattering instrument that makes reliable, reproducible, and non-destructive electrophoretic mobility measurements of macromolecules as small as 2 nm in radius (as well as micron-size nanoparticles) in most aqueous buffers. Included with each Mobius is a copy of DYNAMICS®, the powerful software package for analyzing batch dynamic light scattering and electrophoretic mobility measurements.

The Mobius offers a unique suite of capabilities for mobilityand sizemeasurements of proteins, polymers and nanoparticles. The combination of mobility + size results in a calculation of the nanoparticle’s zeta potential or the protein’s net charge. Thanks to simultaneous dynamic light scattering analysis of molecular/nanoparticle size alongside the mobility measurement, one can monitor changes to the sample in real time and adjust measurement parameters as necessary.

  • Non-destructive analysis of fragile biomolecules
  • Repeatable and accurate measurements in conductive buffers such as physiological saline
  • Simultaneous measurements of size and mobility
  • Automated sample handling or manual measurements
  • Fluorescence blocking filter for sizing of fluorescing nanoparticles such as quantum dots