LCMS-8050
LCMS-8050 offers unparalleled measurement speeds and high-sensitivity performance, redefining LC-MS/MS analysis for multi-component quantitation, reliable qualitative analysis etc. A whole new set of UF Technologies combining sensitivity and speed has been built into the LCMS-8050 to meet the emerging challenges
A New Realm of High-Sensitivity & High-Speed Performance
UF SwitchingTM achieves high-sensitivity performance utilizing a new heated ESI probe and new UFsweeper III collision cell resulting in ionization switching of 5msec.
UF MRMTM high-speed positive/negative ionization switching and high-speed MRM [UF-MRM] maintain data quality and sensitivity.
UF ScanningTM high-speed scan rate obtains high-quality mass spectra, even during high-speed analysis.
UFsensitivity
Advanced Heated ESI probe resulting in Excellent Reproducibility
In order to improve desolvation efficiency, the newly developed heated ESI probe combines a high-temperature gas with the nebulizer spray, assisting in the desolvation of large droplets and facilitating ionization. This development allows for high-sensitivity analysis of a wide range of target compounds.
UF Switching
- Polarity Switching Technology with No Compromise in Quality or Sensitivity.
- Only 5 msec to achieve stable quantitative accuracy with Positive/Negative Ionization switching
- Outstanding throughput and quantitative accuracy
UF Scanning
- Simultaneous, highly reliable quantitative and qualitative Analysis.
- Maintain sensitivity and mass accuracy even at 30,000 u/sec
- Efficient qualitative analysis using Synchronized Survey Scan™
UF MRM
- UFsweeper III high-speed ion transport technology minimizes ion loss even at a dwell time of 8 msec.
- High-speed MRM transitions up to 555 MRMs/sec accelerate laboratory throughput for simultaneous multi-component analyses.
Engineered for Robustness
In addition to speed and sensitivity, Shimadzu designed the LCMS-8050 for robustness to meet the most demanding laboratory requirements and most difficult matrices. The figure below plots the area results from 1000 consecutive analyses of a deproteinized blood plasma sample spiked with alprazolam. The LCMS-8050 achieves excellent reproducibility with a 4.59 % RSD for the area results over the 1000 analyses.
Easy System Maintenance Reduces Downtime
Newly Designed Ionisation Unit.
Designed without cables or tubes, removing the new ionization unit is simple: release a one-touch lever to open the unit and lift it out. In addition, no tools are needed to detach the needles fitted in APCI and DUIS™ units, allowing for easy maintenance.
As with Shimadzu’s other triple quad systems, maintaining the LCMS-8050 is simple. Replacing the desolvation line (DL) and ESI capillary is quick and easy. Additionally, the design allows users to replace the DL without breaking vacuum, providing greater uptime and usability.
Additionally
Lab Solutions Connect
LabSolutions Connect is the smart way to work for all routine laboratories. Simplifying workflows to run samples on the LC-MS/MS with tools to help MRM optimization using its unique features such as
- Tablet like UI for Sample analysis
- Survey Panel view
- New way to view Data
- Optimising better results
LC/MS/MS Method Packages and MRM Libraries
A variety of method packages and MRM libraries, which include analysis conditions such as MRM parameters, enable efficient implementation of simultaneous multi-component analyses. The method parameter list included in these packages can be used to create methods that analyze targeted components only. These packages can save laboratories a great deal of method development time.
