Hyperion+ Imaging System

Imaging Mass Cytometry: Visualize spatial biology. Confidently.

The Hyperion+™ Imaging System allows access to single-cell insights twice as fast as the Hyperion™ Imaging System. This includes a deeper understanding of the intricate spatial relationships of cells, pathways and phenotypes in the tissue microenvironment.

Imaging Mass Cytometry™ (IMC™) with the Hyperion+ Imaging System allows you to uncover important spatial relationships with high-plex imaging of 40-plus markers simultaneously at subcellular resolution.

A precisely directed laser beam focused at 1 μm collects biological samples stained with metal-tagged Maxpar® antibodies from a region of interest. Next, discrete signals from each ionized metal tag are detected with proven CyTOF® technology, based on differences in mass instead of wavelength. Thus, IMC eliminates autofluorescence and achieves uniform staining with minimal background. Large panels can be rapidly designed with little concern about antibody order or label assignment.

The Hyperion+ Imaging System is the ideal solution when you work with heterogeneous biology where assessing key spatial information is critical to driving a deeper understanding of healthy and disease states. This system acquires images twice as fast as the Hyperion Imaging System and can process 100-plus samples per week or 24 tissue microarrays per day. It also improves the limit of detection by at least 1.6x, meaning it better detects dim markers. Use this system to gain a better understanding of immunotherapy responses that could ultimately help extend patient lives. It can also be used to get faster results when you have a high number of samples or large cohort studies.