HS-10 Headspace Sampler for GC

The HS-10 headspace sampler for Gas Chromatography is highly cost efficient, yet is equipped with advanced features such as a mixing function and the ability to heat-ahead the sample vials waiting for analysis. This instrument is the perfect platform for the analysis of residual pharmaceutical solvents and trace VOCs in wastewater.

Outstanding Reproducibility

Excellent reproducibility can be obtained, thanks to high-accuracy flow rate control by electronic flow controllers (AFC and APC), and a thermostatic vial chamber with a uniform temperature distribution

The temperature in the thermostatic vial chamber is uniform. As a result,

Reproducibility for 0.4 % Ethanol 2.0 % (n = 10)

USP<467>Analysis of Residual Pharmaceutical Solvent

Residual solvents in pharmaceuticals are strictly controlled, and are categorized as Class 1 to Class 3 depending on the risk they pose to human health. The headspace GC method prescribed in USP<467>is utilized for the analysis of residual solvents. Class 1 Procedure A requires a S/N ratio ≥5 for 1,1,1-trichloroethane and a S/N ratio ≥3 for all peaks, while Class 2A requires a resolution ≥1.0 for acetonitrile and methylene chloride. The HS-10 satisfies all of these requirements.

1: 1,1-Dichloroethene 5: 1,2-Dichloroethane
2: 1,1,1-Trichloroethane 6: Acetonitrile
3: Carbon tetrachloride 7: Methylene chloride
4: Benzene
GL Sciences Inc.  InertCap 467, 0.32mmI.D.×30m df=1.80um

Analysis of VOCs in Water

This is an example of the analysis of 10 μg/L (10 ppb) VOCs in water using the HS-10 and an ECD. The VOCs in water can be measured with excellent reproducibility due to the high thermal stability of the HS-10.

                 Reproducibility of 10 ppb VOCs RSD % (n = 5)
1: 1,1-Dichloroethene 2.1 10: 1,2-Dichloropropane 1.9
2: Dichloromethane 2.0 11: Bromodichloromethane 2.4
3: trans-1,2-Dichloroethene 2.6 12: cis-1,3-Dichloropropane 1.6
4: cis-1,2-Dichloroethene 2.3 13: trans-1,3-Dichloropropane 1.7
5: Chloroform 2.1 14: 1,1,2-Trichloroethane 2.2
6: 1,1,1-Trichloroethane 2.6 15: Tetrachloroethene 3.4
7: Carbon tetrachloride 3.3 16: Dibromochloromethane 2.1
8: 1,2-Dichloroethane 1.9 17: Bromoform 1.6
9: Trichloroethene 2.7 18: 1,4-Dichlorobenzene 2.8

Overlap Analysis

During a GC analysis, the HS-10 will take the next vial and move it to the vial heater. There, it can incubate for a specified time and be ready for injection when the previous analysis cycle has ended.