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Multi-Omics Method Package SpincoTech

The Multi-omics Analysis Package, developed for metabolic engineering applications, provides the ability to automatically generate metabolic maps and perform a variety of data analysis for the vast data generated in fields like metabolomics, proteomics and flux analysis. It offers a powerful platform to support drug discovery, bioengineering and other life science research applications.

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Dramatically reduces the amount of work required for bottleneck processes of analyzing and visualizing data, such as displaying data on a metabolic map and analyzing correlations.

In combination with various other software (called gadgets) connected on the GARUDA™ platform, it offers optimal workflows for multi-dimensional analyses.

The software includes various data processing gadgets which connect with corresponding data analysis gadgets, providing a seamless, connected experience of a single software program. It is designed to work in combination with various Shimadzu databases prepared with “Ready-to-Use Methods” for everything from sample pretreatment to analytical conditions, which ensures the entire process flow, from obtaining mass spectrometer measurements to data analysis, can be performed smoothly.

In the Multi-omics Analysis Package, we provide the data analysis software developed based on tools (gadgets) that have been released on the GARUDA open research platform, which is mainly managed by The Systems Biology Institute, Japan (SBI).

Multi-omics Analysis Package includes various data processing gadgets which connect with corresponding data analysis gadgets, providing a seamless, connected experience of a single software program. Furthermore it is designed to work in combination with various Shimadzu database, which ensures the entire process flow, from obtaining mass spectrometer measurements to data analysis, can be performed smoothly.

Changes in metabolite levels in a cell culture medium over time were measured using a GC-MS system. Acquired data was analyzed using the Multi-omics Analysis Package and metabolite changes were visualized by displaying them on a metabolic map.

The Multi-omics Analysis Package is based on software tools (called gadgets) that have been released on the GARUDA platform – an open research platform, developed by the GARUDA Alliance led by The Systems Biology Institute, Japan (SBI).

Volcano Plot
A tool that combines a t-test (statistically significant difference) and a fold-change (Example: Difference in mean value such as 2 times or 1/2) to visualize the differences between the two groups. The Volcano Plot gadget developed by Shimadzu is included in the package.

VANTED
Tool maintained at University of Konstanz, Germany, for visualization and analysis of networks across different data sets. (GARUDA support was developed at Monash University)

Cytoscape
Bioinformatics tool developed by the Cytoscape Consortium, used to visualize metabolic pathways, to integrate gene expression profiles with related data, and so on. It is especially useful for analyzing networks and visualizing correlations.