Method Scouting System

Maximizing Efficiency for Method Development

Usually when scouting for the best analytical conditions, a method has to be created every time the
column or mobile phase is switched. For example, 100 combinations of analytical conditions leads to 100 method files, not
only creating a huge amount of labor but also increasing the risk of operational errors. Method scouting System is intuitive to operate and can automate these changes in analytical conditions, allowing you to use resources efficiently.

Maximizing Efficiency for Method Development

Method scouting can now be performed with Shimadzu’s diverse LC product line-up. Choose the system suited to your laboratory environment, whether for SFC investigations or simple investigations on compact systems. Here are the examples.

N-Series Method Scouting System

• Investigate analytical conditions with automated switching of columns and mobile phases
• Compatible with systems including 130 MPa UHPLC models or UHPLC-like models with method transfer.

Supercritical Fluid Chromatograph Nexera/UCs UHPLC/SFC Switching System

• Optimized for method investigation of chiral compounds
• Also compatible with LC/SFC switching, and can investigate various separation modes

AI-Series Method Scouting

• Saves costs in transferring to routine testing
• Space-saving, low-cost design

Combine Method Scouting System with Method Scouting Solution dedicated software to achieve substantial efficiency improvements across all operations from method creation to data acquisition and analysis.

The mobile phase blending function in Method Scouting System allows you to quickly adjust the salt concentration, pH, and organic solvent ratio on-line using only a few pre-prepared solvents, and quickly search for suitable conditions. This significantly reduces the time required to prepare and evaluate mobile phases. The integrated i-Series LC system can also perform different types of mobile phase blending, two for water-based and two for organic solvents, using a low-pressure gradient.

Usually when method scouting, a method has to be created every time the column or mobile phase is switched. For example, 100 combinations of analytical conditions leads to 100 method files, not only creating a huge amount of labor but also increasing the risk of operational mistakes. Method Scouting System is intuitive to operate and can automate these changes in analytical conditions, allowing you to use your resources more efficiently.

Optimization and Robustness Evaluation

• Simple to Set Conditions for Optimization
• Efficient Robustness Evaluations
• Improve Efficiency Even With Standard LCs
• Seamless Method Migration with LabSolutions™ CS

Once the optimal conditions are determined, they may be applied as general-purpose analysis conditions and transferred to other working departments. The data needs to be managed over long time periods and retrieved smoothly when needed. The combination of LabSolutions CS and Method Scouting Solution not only makes the method development process more efficient, but also streamlines a series of workflow tasks from reporting results to other departments to transferring methods.

Applications

• Productivity Improvements for Method Scouting Process

Labor-Saving Mobile Phase Blending

The mobile phase blending function in Method Scouting System allows you to quickly adjust the salt concentration, pH, and organic solvent ratio on-line using only a few pre-prepared solvents, and quickly search for suitable conditions. This significantly reduces the time required to prepare and evaluate mobile phases. The integrated i-Series LC system can also perform different types of mobile phase blending, two for water-based and two for organic solvents, using a low-pressure gradient. Furthermore, there are many optimisations incorporated into method scouting software which makes it a vital requirement in every industry.