Advanced i-Series High Performance Liquid Chromatograph
Nexera XS inert Bio-inert UHPLC
Advanced i-Series Gel Permeation Chromatograph
N-Series, The NextGen UHPLC
Method Scouting System
Amino Acid Analysis System
Nexera Organic Acid Analysis System
Nexera Voglibose Analysis System
Nexera™ FV
P-Series All Round HPLC
Liquid Chromatography-Analytical
Detectors
SEDEX 85LT Low-Temperature Evaporative Light Scattering Detector for HPLC
SEDEX LT-ELSD LC Low-Temperature Evaporative Light-Scattering Detector
Sedex LT-ELSD Model 100 LT Universal Detector for HPLC
Beta-RAM Model 6 World’s leading Radio-HPLC Flow Detector
Flow-RAM Radio HPLC Detector
Scan-RAM radio-TLC
DECADE Elite Electrochemical Detector
Fluorescence Detector
Photodiode Array Detector
Refractive Index Detector
Onyx PCX Post-Column
Derivatization Instrument for HPLC
Vector PCX Postcolumn Derivatization System
UVE™ Photochemical Reactor
Nexera™ FV
Taking Online Dissolution Testing in to the New Era of Ultra High Performance Chromatography
Dissolution tests are widely used in original pharmaceuticals development and quality control and for bioequivalence tests in generic drugs.
The Nexera FV provides substantial labor savings by automating processes ranging from the dispensing of dissolution media to data acquisition and data analysis.
In addition, the system is based on the N-Series, renowned for its speed, sensitivity, and stability. Now you can quickly obtain reliable dissolution test results. The Nexera FV can also be used as a standard UHPLC system, ensuring high laboratory throughput.
Provides Labor Savings and Faster Speeds in Dissolution Testing
System Configuration for Online
- Dissolution Testing With the Nexera FV, the dissolution tester and the autosampler are connected online, so everything is automated from sampling to dilution to data acquisition and analysis. As a result, there is less test-related work for the operator, and a subsequent increase in processing throughput.In addition, there is no manual dispensing of samples, ensuring reliable results.
Enables Testing of Quickly Dissolving Samples
Two Analysis Modes Promote Faster Dissolution Testing
- Direct Injection Analysis Mode: Exclusively with the Nexera SystemThe dissolution medium is directly loaded and analysed. This is effective if the analysis of the number of vessels finishes before the next sampling interval.
- Fraction Analysis Mode: For Confirmation of Dissolution Profiles at Short Sampling IntervalsThis is used for tests in which the sampling interval is short. The N-series autosampler compatible with sampling intervals as short as five minutes. In addition, up to 768 samples can be fractionated, making this mode effective when the dissolution quantity is large and dilution will be required. In addition, up to 768 samples can be fractionated at once.
Reliable Performance Expands the Range of Choices
- Compatible with High-Concentration Samples Requiring Dilution
- One System Plays Two Roles, Significantly Improving the Throughput of the Testing Lab
- Long-Lasting Consumables Provide for High Cost-Effectiveness
Substantial Improvements in Work Scheduling
Special Software Makes Testing Preparation More Efficient
- DT-Solution Software Supports the Creation and Implementation of Test SchedulesWith dissolution tests, one of the most labor-intensive processes is establishing a batch schedule for the test. The custom DT-Solution software eases the burden. With this software, the user can configure all the required information in a single window. Then, click a single button to automatically generate a batch schedule in LabSolutions™ software so that testing can start. In dissolution tests performed with the Nexera FV, preparation time is minima
- Rapid Confirmation of Test Results and Automatic Generation of ReportsThe browser function built into LabSolutions is convenient for assessing changes in the chromatogram over time. Multiple data sets can be displayed simultaneously in a single window, so the data can be compared at a glance. In addition, the creation of reports on can be completely automated with the multi-data report function. When the test finishes, a result table, pivot graphs, and test pass/fail judgments for each component are created automatically, so the test results can be rapidly confirmed.
