Advanced i-Series High Performance Liquid Chromatograph

Amid increasing calls for improved work efficiency and a more flexible working style, ideas of LC analysis are changing. The time has come for an Ai Living LC that delivers rugged, reliable results with less frequent interaction by the analyst. The i-series is the perfect system for a number of applications such as qualitative and quantitative analysis in a wide range of industries such as pharmaceuticals, chemicals, foods among many others. Spinco Biotech has been the most favoured Ai Living LC supplier in India, having crossed many milestons in supporting users of Shimadzu HPLCs since 1983.

Ai-Series Living LC provides a high level of basic performance with improved ease-of-use.  Imbibing the several world-class features, the system provides many new innovations

• Autosampler pretreatment function enabling 2-100 times dilution,
• Spiking set volumes of internal standards or reaction reagents,
• Coinjection for peak shape improvements
• Dedicated auto-prep applications such as pre-labelled amino acid analyses,
• Wider column oven temperature covering from RT-12 Deg C to 90 Deg C enabling quantitation analysis of                                         D-Mannitol as per Pharmacopoeial recommendations
• Enhancing data integrity functions such as completely blocking local operation through touch panel

Innovative

Remote instrument operation and monitoring allow analyses to be performed remotely, thereby reducing the time spent in the laboratory.

Intelligent

Software integration ensures both data reliability and improved work efficiency.

Intuitive

Intuitive operation ensures an efficient workflow.

Innovative

Automation and Remote Operation/Monitoring
Encourage a New Style of work

Analytical Intelligence functions, such as FlowPilot and mobile phase monitoring, and LabSolutions™ Direct can provide an automated workflow together with remote operation and monitoring from instrument startup to analysis completion. Automated workflows incorporate the work-style habits of experienced analysts. The result is reliable data collected over extended periods.

Using Networks for More Improvements in Work Efficiency LabSolutions CS allows remote operation and monitoring of all instruments on the analytical network from any locations, even from home. Analysis data and reports are managed on a centralized database where administrative authorization allows managers to assign appropriate operational restrictions to operators, depending on their expertise and rank.

Mobile Phase Monitoring

Mobile Phase Monitor enables real-time, gravimetric monitoring of mobile phase levels to ensure maximum up time using both large (5L) and small (1L) reservoirs. Levels for mobile phase or autosampler rinse solution may be monitored up to six containers. The containers can also be checked remotely from a smart device (PC/iOS/Android). The system operation can be performed round-the-clock through weekend automation under highly secure and compliant environment.

Mobile Phase Flowrate Control Function

Smart Flow Control Protects Columns which can be damaged by instant ‘pump starts’ and extreme gradient changes, especially with columns packed with polymeric phases. Smart Flow Control (FlowPilot) increases the flow rate gradually to the method set point according to the status of the column oven, extending the life of your columns.

Remote Operation/Monitoring Function

Take Control of Instruments from Outside the Laboratory

Using LabSolutions Direct, analysts can operate instruments remotely and implement pre-configured methods and batch analyses using the web browser of a computer or a smart device. Instrument status and chromatograms can also be monitored remotely to reduce the time and labor required to travel to and from the laboratory for improved work efficiency.

Intelligent

i-PeakFinder Automatic Peak Integration Function

Process Large Volumes of Data with High Precision in a Single Step

Manual integration of unresolved peaks is a labor-intensive process and is prone to inconsistent results depending upon the experience level of the user. Shimadzu’s proprietary i-PeakFinder peak integration algorithm is the perfect for such situations. i-PeakFinder processes large volumes of data with high precision in a single step, saving a lot of time and increasing the consistency of results.

ACTO Method Migration Support Function

Considering Instrument Replacement and Method Migration

Migrating a test method (analytical conditions or method) from one instrument to another while obtaining the same chromatogram can be a challenging process. The Ai-Series is designed with the same internal system volumes as the previous models of Shimadzu and competitor systems to ensure system compatibility and data reproducibility. The Analytical Condition Transfer and Optimization (ACTO) function also adjusts gradient start time automatically, so analysts can make adjustments to separations obtained by gradient analysis easily.

i-PDeA II Peak Deconvolution Function

Tools to Help in Dealing with Difficult Separations

The i-PDeA II peak deconvolution function uses a multivariate curve resolution alternating least squares (MCR-ALS) method to enable qualitative and quantitative analysis of peaks not fully separated by the column. The i-PDeA II can also be used to check the purity of target peaks. (Only available when using a PDA detector and LabSolutions.)

Intuitive

Auto-Validation Function

Stable Operation Assured with Smart System Startup and shutdown

Starting Auto-validation

Procedures, mobile phases, and other information necessary for validation are displayed on the screen, allowing you to perform inspections by simply following the instructions.

Creating a System Check Report

Validation results can be viewed from the Ai-Series main unit. Validation results can also be output in a report format from a workstation.

Dual-Temperature Control with TC-Optics and Flow Cells

Ultra-Low Carryover Performance Enables High-Sensitivity Analysis