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Bioprocessing Upstream

Getinge bioreactors, spanning from 250 mL to several thousand liters, provides validated solutions for cell and microbial cultures in the biopharmaceutical R&D sector. The ChemoMetec NucleoCounter® accurately counts diverse cell types from seeding to advanced production, facilitating offline cell counting. Timegate Instruments electrical gating with pulsed picosecond lasers and CMOS-SPAD (Single Photon Avalanche Diode) detectors for Raman Spectra enables real-time monitoring in bioprocessing without manual sampling.


Shimadzu HPLC offers unparalleled repeatability crucial for precise peptide mapping, ensuring consistent analysis of elution patterns. The Nexera XS inert delivers superior performance, overcoming adsorption challenges for enhanced accuracy, sensitivity, and separation of amino acids, oligonucleotides, glycans, charge variations, aggregation analysis, and peptide fragments.


Shimadzu benchtop MALDI-TOF measures the molecular weights of nucleic acids, proteins, peptides, polymers or oligonucleic acids, as well as address applications such as intact mass, disulphide linkages, glycans, biomarkers, post translational modifications, oligonucleotides, and amino acid sequencing with no performance compromise.


Shimadzu Q-TOF mass spectrometer, paired with Protein Metrics software, enables precise mass analysis of monoclonal antibodies with high sensitivity and resolution, ensuring consistently accurate results. Its applications extend to quantitative analysis of biopharmaceuticals, impurity detection, and peptide mapping.

Triple Quadrupole LC-MS

Shimadzu LCMS 80XX series with UF technologies provides maximum sensitivity and speed for analyzing antibody drugs, glycan profiling, peptide mapping, spent media, and qualitative/quantitative assessments of culture media, bovine serum, and metabolomic analysis of culture supernatant and body fluids.

Method Packages

Complementing the biopharmaceutical workflows, the method packages from Shimadzu are tailored to specific applications with greatest ease of use including Cell Culture Profiling, lipid mediators, primary metabolites enabling multiomics analysis possible.


Technobis Crystalline System, equipped with a real-time digital camera and AI capabilities, efficiently assesses protein solution phase transitions, including crystallization, amorphous aggregate formation, protein stability and liquid-liquid phase separation.

Process Monitoring

SOPAT’s inline measurement gauges gas droplets, optimizing sparging rate and tip speed in both process development and real-time monitoring during manufacturing, while Enwave’s Raman analyzer delivers high-performance, real-time, multi-parameter monitoring for cell culture and fermentation allowing continuous measurements, improving bioprocess understanding.

Homogenization & Decontamination

Kinematica HPH offers efficient cell lysis with an innovative chamber and optimized plunger, allowing easy automated cleaning and sterilization. The versatile Atomix suits small-scale development to full-scale manufacturing, customizable for seamless integration with process equipment.

Subvisible Particle Analysis & Identification

Subvisible particle analysis is of the utmost importance, as it allows us to accurately characterize large visible contaminants and ensure patient safety. Halo Labs Aura platform, powered by BMI, provides a USP <788> compendial method that is rapid and robust.

Multiplexed Immunoassays

Meso Scale Discovery’s immunoassay platform quantifies proteins using Electrochemiluminescence detection with SULFO-TAGTM labels on MULTI-ARRAY and MULTI-SPOTTM plates, spanning biomarker discovery, immunogenicity, pre-clinical /clinical studies, vaccine development, personalized medicine, and assay development.

Field-Flow Fractionation (FFF)

Postnova FFF for the separation and characterization of nano to lower micrometer-sized analytes. Utilizing flow-based separation methods, FFF employs detectors like Refractive Index, UV, or Fluorescence for concentration determination, and MALS or DLS for sizing and molecular weight determination.

Microfluidic Modulation Spectroscopy (MMS)

RedShiftBio MMS analytical characterization technique provides in-depth secondary structural protein information in a single automated analysis for five measurements such are aggregation, quantitation, structure, stability and similarity.

Parenteral Leak Detection

PTI’s microcurrent-based High Voltage Leak Detection, compliant with USP <1207>, ensures Container Closure Integrity (<1 micron) for vials, ampoules, PFS, and cartridges. Validated for use with low conductivity liquids and large protein-based molecules.

Protein Sequencer

Shimadzu EDMAN based N – Terminal Sequencing.